This meme is using humor to comment on the scientific pursuit to explain natural phenomena without invoking deities or the supernatural. The phrase 'THE SCIENTISTS ARE WORKING ON IT OF THE GAPS' is likely a play on the 'God of the gaps' argument, which suggests that gaps in scientific knowledge are evidence of God's existence. The juxtaposition of the person in the image, who appears to be in a prayerful pose, with a twist on the religious phrase 'Thy kingdom come' to 'Thy kingdomless come' implies a satirical take on the concept of a world where science provides all answers, effectively creating a 'kingdom' without gods.