People might find this meme funny or clever because it is a play on words referencing the popular video game phrase 'I used to be an adventurer like you, then I took an arrow to the knee' from The Elder Scrolls V: Skyrim. The image shows a pager with a modified message that humorously substitutes 'an arrow' with 'the liver,' possibly implying a humorous spin to a medical context or a drinking joke.