The meme features an image of two women from an older era riding bicycles on cobblestones. The humor comes from the double entendre of the first woman's statement, 'I've never come this way before!' which could be interpreted as navigating a new route or experiencing a new sensation due to the cobblestone road. The second woman's response, 'It's the cobblestones,' while literally referring to the bumpy road, contributes to the innuendo and the humor.